2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. mGluR
  5. mGluR5 Isoform
  6. mGluR5 Activator

mGluR5 Activator

mGluR5 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-120727
    VU0364289
    		Activator 99.52%
    VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP (HY-14609A) site), with an EC50 of 1.6 µM. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research.