2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Phosphomannose Isomerase (PMI)
  5. Phosphomannose Isomerase (PMI) Inhibitor

Phosphomannose Isomerase (PMI) Inhibitor

Phosphomannose Isomerase (PMI) Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-112945
    MLS0315771
    		Inhibitor 99.46%
    MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.
  • HY-138802
    ML089
    		Inhibitor 99.86%
    ML089 is a potent, selective, and orally available phosphomannose isomerase (PMI) inhibitor with an IC50 of 1.3 µM. ML089 can be used for the research of congenital disorder of glycosylation Ia.
  • HY-124890
    Thr101
    		Inhibitor 99.36%
    Thr101 is an inhibitor (IC50=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia).