2. Signaling Pathways
  3. Autophagy
    Neuronal Signaling
  4. PINK1/Parkin
  5. PINK1/Parkin Inhibitor

PINK1/Parkin Inhibitor

PINK1/Parkin Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-163562
    JYQ-164
    		Inhibitor
    JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research.