2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Poly(ADP-ribose) Glycohydrolase (PARG)
  5. Poly(ADP-ribose) Glycohydrolase (PARG) Inhibitor

Poly(ADP-ribose) Glycohydrolase (PARG) Inhibitor

Poly(ADP-ribose) Glycohydrolase (PARG) Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-137924
    JA2131
    		Inhibitor ≥99.0%
    JA2131 is a small molecular inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG) (IC50=0.4 μM). JA2131 regulate DNA damage responses, causes replication fork stalling and cancer cell death.
  • HY-156881
    PARG-IN-4
    		Inhibitor 98.86%
    PARG-IN-4 (Formula (A)) is an orally active and cell-permeable PARG inhibitor. PARG-IN-4 effectively inhibits tumor growth in mouse models. PARG-IN-4 can be used in cancer research.
  • HY-164757
    PARP-1-IN-32
    		Inhibitor
    PARP-1-IN-32 (compound 15) is a poly (ADPribose) polymerase-1 (PARP-1) inhibitor. PARP-1-IN-32 can be used in cancer research.
  • HY-122041
    Ethacridine
    		Inhibitor
    Ethacridine is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor and an activator of the transcriptional coactivator. Ethacridine induces thyroid cancer cells apoptosis and promotes differentiation in thyroid follicular cells.