2. Signaling Pathways
  3. Stem Cell/Wnt
  4. SDCBP
  5. SDCBP Inhibitor

SDCBP Inhibitor

SDCBP Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-156247
    IVMT-Rx-3
    		Inhibitor
    IVMT-Rx-3 is a inhibitor of SDCBP targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin. IVMT-Rx-3 blocks MDA-9/Syntenin interaction with Src, reduces NF-κB activation, and inhibits MMP-2/MMP-9 expression. IVMT-Rx-3 inhibits Melanoma Metastasis[1]
  • HY-P10331
    KSL 128114
    		Inhibitor
    KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin.
  • HY-149204
    SYNTi
    		Inhibitor
    SYNTi is a PDZ domain inhibitor targeting the syndecan/syntenin protein-protein Interaction. SYNTi exhibits an IC50 value of 400 nM and ligand efficiency (LE) value of 0.24. SYNTi can be used for breast cancer research.