2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Transglutaminase
  5. Transglutaminase Inhibitor

Transglutaminase Inhibitor

Transglutaminase Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-129225
    WRR139
    		Inhibitor 99.71%
    WRR139 is a peptide vinyl sulfone involving in disease processes such as inflammation and cancer. WRR139 is also a cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1 inhibitor. WRR139 enhances Carfilzomib cytotoxicity against cancer cells.
  • HY-128595
    MT-4
    		Inhibitor 98.85%
    MT-4 is a derivative of a tissue transglutaminase (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel.