2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. AA29504

AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases .

For research use only. We do not sell to patients.

AA29504 Chemical Structure

AA29504 Chemical Structure

CAS No. : 945828-50-2

Size Price Stock Quantity
5 mg USD 328 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
10 mg USD 524 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
25 mg USD 943 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
50 mg   Get quote  
100 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

AA29504 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases [1].

In Vitro

AA29504 (0.1, 1, 10, 100 μM, 72 h) can open the Kv7 voltage-gated K+ channels (KCNQ) in Xenopus oocytes [1].
AA29504 (1 μM) positively regulates GABAA receptors expressed in Xenopus oocytes, EC501.4 μM[1] .
AA29504 (1 μM, 10 s) significantly enhances the gaboxadol-mediated current in pyramidal neurons of the prefrontal cortex[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AA29504 Related Antibodies
In Vivo

AA29504 (0.5, 2 or 4 mg/kg, subcutaneously injection) has antianxiety effects in male SD (Spraguee Dawley) rats[1].
AA29504 (4 mg/kg, subcutaneous injection) significantly weakenes the motor coordination of male SD rats under the synergistic effect of alcohol [1].
AA29504 (2.5, 5 and 10 mg/kg, subcutaneously injection) has therapeutic effect on amygdala ignited seizures in male Wistar rats [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Spraguee Dawley rats [1]
Dosage: 0.5, 2 or 4 mg/kg
Administration: Subcutaneous injections
Result: Reduced the number of vocalizations at 4 mg/kg and reversed partially the freezing behavior at 2 mg/kg.
Animal Model: Male Spraguee Dawley rats [1]
Dosage: 4 mg/kg
Administration: Subcutaneous injections
Result: Reduced the time the rats stayed on the rotarod at 4 mg/kg.
Animal Model: Male Wistar rats [1]
Dosage: 10 mg/kg
Administration: Subcutaneous injections
Result: Reduced from 4.9 to 2.0 in amygdala kindled seizures response.
Molecular Weight

327.42

Formula

C19H25N3O2
CAS No.
SMILES

O=C(NC1=CC=C(NCC2=C(C)C=C(C)C=C2C)C=C1N)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

AA29504 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AA29504945828-50-2AA 29504AA-29504GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorXenopus oocytespyramidal cells ofprefrontal cortexGABAA receptorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
AA29504
Cat. No.:
HY-103522
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.