AcrAP1  (Synonyms: AP1-Z1)

AcrAP1 (AP1-Z1) is an antimicrobial peptide found in the venom of the Arabian scorpion (Androctonus crassicauda). AcrAP1 has antimicrobial activity and can inhibit the growth of Gram-positive and Gram-negative bacteria as well as yeast. AcrAP1 exerts antitumor activity by promoting apoptosis of cancer cells and inhibiting angiogenesis. AcrAP1 can be used in cancer therapy research^[1].

1960.36

C₉₇H₁₅₀N₂₂O₂₁

Phe-Leu-Phe-Ser-Leu-Ile-Pro-His-Ala-Ile-Ser-Gly-Leu-Ile-Ser-Ala-Phe-Lys-NH2

FLFSLIPHAISGLISAFK-NH2

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(NCC(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=CC=C5)N

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Ma R, et al. In vitro and MD simulation study to explore physicochemical parameters for antibacterial peptide to become potent anticancer peptide[J]. Molecular Therapy-Oncolytics, 2020, 16: 7-19.  [Content Brief]