2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Endogenous Metabolite Calmodulin
  4. Acremonidin A

Acremonidin A is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremonidin A binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 19.40 nM.

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Acremonidin A Chemical Structure

Acremonidin A Chemical Structure

CAS No. : 701914-77-4

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Acremonidin A Related Antibodies

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Description

Acremonidin A is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremonidin A binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 19.40 nM[1].

IC50 & Target[1]

Microbial Metabolite

 

Molecular Weight

614.55

Formula

C33H26O12
CAS No.
SMILES

CC(O[C@@H](C1=CC(C)=CC(O)=C21)[C@](CC(C3=C4O)=CC(O)=C4C(C(C(O)=CC=C5O)=C5C(OC)=O)=O)(C=C[C@]3([H])C6=O)C6=C2O)=O
Structure Classification
Initial Source

filamentous fungi
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Acremonidin A Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acremonidin A701914-77-4Endogenous MetaboliteCalmodulinCaMCalcium-modulated proteincalmodulin inhibitorhCaM biosensorInhibitorinhibitorinhibit

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