2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Adinazolam

Adinazolam  (Synonyms: U 41123)

Cat. No.: HY-A0198 Purity: ≥99.0%
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Adinazolam (U 41123) is a benzodiazepine agonist. Adinazolam, a triazolobenzodiazepine, has dual anxiolytic and antidepressant activities.

For research use only. We do not sell to patients.

Adinazolam Chemical Structure

Adinazolam Chemical Structure

CAS No. : 37115-32-5

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1 mg USD 375 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Adinazolam:

Adinazolam Related Antibodies

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Description

Adinazolam (U 41123) is a benzodiazepine agonist. Adinazolam, a triazolobenzodiazepine, has dual anxiolytic and antidepressant activities[1].

In Vivo

Adinazolam (6 mg/kg) increases shuttlebox avoidance acquisition in male Sprague-Dawley rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats weighing 409±30 g[2]
Dosage: 6 mg/kg
Administration: Administered i.p. in 2 mL/kg
Result: Increased avoidance acquisition in 195% as compared to control animals.
Molecular Weight

351.83

Formula

C19H18ClN5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C)CC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=NC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 1 mg/mL (2.84 mM; Need ultrasonic and warming)

H2O : 1 mg/mL (2.84 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8423 mL 14.2114 mL 28.4228 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 2.8423 mL 14.2114 mL 28.4228 mL 71.0570 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Adinazolam Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adinazolam37115-32-5U 41123U41123U-41123GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid Receptorantihistaminepiperazineanti-motionsicknessHuntingtonInhibitorinhibitorinhibit

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