2. MAPK/ERK Pathway
  3. p38 MAPK
  4. AKP-001

AKP-001 is an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). AKP-001 can inhibit the production of inflammatory cytokines and can be used for research in rheumatoid arthritis and inflammatory bowel disease.

For research use only. We do not sell to patients.

AKP-001 Chemical Structure

AKP-001 Chemical Structure

CAS No. : 897644-83-6

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AKP-001 Related Antibodies

Top Publications Citing Use of Products

View All p38 MAPK Isoform Specific Products:

View All Isoforms
p38 MAPK p38α p38β MAPK13 p38δ p38γ

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Description

AKP-001 is an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). AKP-001 can inhibit the production of inflammatory cytokines and can be used for research in rheumatoid arthritis and inflammatory bowel disease[1].
Molecular Weight

426.80

Formula

C21H13ClF2N4O2
CAS No.
SMILES

O=C(NC1=C(C2=NC=NC=C2)C(C3=CC=C(F)C=C3)=NO1)CC4=C(F)C=CC=C4Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AKP-001 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKP-001897644-83-6AKP001AKP 001p38 MAPKinflammatory cytokinesrheumatoid arthritisinflammatory bowel diseaseInhibitorinhibitorinhibit

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HY-100278
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