2. Metabolic Enzyme/Protease
  3. Elastase
  4. Ala-Ala-Pro-Val-chloromethylketone

Ala-Ala-Pro-Val-chloromethylketone  (Synonyms: AAPV-CMK)

Cat. No.: HY-P3648
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Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases.

For research use only. We do not sell to patients.

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Ala-Ala-Pro-Val-chloromethylketone Chemical Structure

Ala-Ala-Pro-Val-chloromethylketone Chemical Structure

CAS No. : 90105-47-8

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Ala-Ala-Pro-Val-chloromethylketone Related Antibodies

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Description

Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases[1].

In Vivo

Methoxysuccinyl-Ala-Ala-Pro-Val chloromethylketone (oropharyngeal aspiration; 85 μM, 40 μL; days 1, 4, and 7) blocks NE-induced cupped cell chemotaxis and significantly reduces Muc5ac gene and protein expression in male Balb/c mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

388.89

Formula

C17H29ClN4O4
CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Ala-Ala-Pro-Val-chloromethylketone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ala-Ala-Pro-Val-chloromethylketone90105-47-8AAPV-CMKElastaseneutrophil elastaseNEinflammatory airway diseasesInhibitorinhibitorinhibit

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