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Alectinib analog  (Synonyms: CH5424802 analog; RO5424802 analog; RG7853 analog)

Cat. No.: HY-W814315
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Alectinib analog (CH5424802 analog) is a selective ALK inhibitor with activity in blocking resistance gating mutations. The synthetic optimization of alectinib analog allows it to be combined with specific peptides to improve the ability to target cancer cells. Alectinib analog exhibits low micromolar IC50 values in antiproliferation and shows good cytotoxic effects. The inhibitory activity of alectinib analog is closely related to its stability and release of active ingredients. Alectinib analog demonstrated the ability to inhibit vascular septal length or width in an in vivo zebrafish model.

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Alectinib analog Chemical Structure

Alectinib analog Chemical Structure

CAS No. : 1256577-71-5

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Alectinib analog Related Antibodies

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Description

Alectinib analog (CH5424802 analog) is a selective ALK inhibitor with activity in blocking resistance gating mutations. The synthetic optimization of alectinib analog allows it to be combined with specific peptides to improve the ability to target cancer cells. Alectinib analog exhibits low micromolar IC50 values in antiproliferation and shows good cytotoxic effects. The inhibitory activity of alectinib analog is closely related to its stability and release of active ingredients. Alectinib analog demonstrated the ability to inhibit vascular septal length or width in an in vivo zebrafish model[1].

Molecular Weight

454.56

Formula

C28H30N4O2
CAS No.
SMILES

N#CC1=CC(NC2=C3C(C4=CC=C(N5CCC(CC5)N6CCOCC6)C=C4C2(C)C)=O)=C3C=C1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Alectinib analog Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alectinib1256577-71-5CH5424802RO5424802RG7853CH 5424802CH-5424802RO 5424802RO-5424802RG 7853RG-7853OthersInhibitorinhibitorinhibit

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