2. TGF-beta/Smad
  3. TGF-β Receptor
  4. ALK5-IN-25

ALK5-IN-25 (compound EX-02) is a potent ALK-5 inhibitor with an IC50 ≤10 nM.ALK5-IN-25 also inhibits ALK-2 (selectivity ALK2/ALK5≤10). ALK5-IN-25 can be used for the research of cancer.

For research use only. We do not sell to patients.

ALK5-IN-25 Chemical Structure

ALK5-IN-25 Chemical Structure

CAS No. : 2785430-81-9

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ALK5-IN-25 Related Antibodies

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ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B

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Description

ALK5-IN-25 (compound EX-02) is a potent ALK-5 inhibitor with an IC50 ≤10 nM.ALK5-IN-25 also inhibits ALK-2 (selectivity ALK2/ALK5≤10). ALK5-IN-25 can be used for the research of cancer[1].

IC50 & Target

ALK5

≤10 nM (IC50)

ALK2

 

Molecular Weight

430.48

Formula

C23H23FN8
CAS No.
SMILES

CC1=C(F)C=CC2=C(NC3=NC(NC4=CC=C(N5CCNCC5)C=C4)=NC=C3)C=NN=C12
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ALK5-IN-25 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALK5-IN-252785430-81-9TGF-β ReceptorTransforming growth factor beta receptorscancerATCCCCL-136SMAD reporter vectorInhibitorinhibitorinhibit

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