1. Metabolic Enzyme/Protease
  2. Aldose Reductase
  3. ALR1/2-IN-1

ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) and aldose reductase (ALR2) inhibitor with IC50 values of 3.26 μM and 3.06 μM against ALR1 and ALR2, respectively. ALR1/2-IN-1 shows anticancer activity.

For research use only. We do not sell to patients.

ALR1/2-IN-1 Chemical Structure

ALR1/2-IN-1 Chemical Structure

CAS No. : 2419233-57-9

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Description

ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) and aldose reductase (ALR2) inhibitor with IC50 values of 3.26 μM and 3.06 μM against ALR1 and ALR2, respectively. ALR1/2-IN-1 shows anticancer activity[1].

IC50 & Target

IC50: 3.06 μM (ALR2), 3.26 μM (ALR1)[1]

In Vitro

ALR1/2-IN-1 (Compound 6e) (100 µM) shows cytotoxic potential with 32.9 ± 3.26% inhibition against cervical carcinoma cells HeLa[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

434.49

Formula

C18H18N4O5S2

CAS No.
SMILES

O=C(NC1=CC=CC=C1OC)CSC2=NN=C(C3=CC=CC=C3NS(=O)(C)=O)O2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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ALR1/2-IN-1
Cat. No.:
HY-147977
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