AMC Arachidonoyl Amide (Synonyms: AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide)

Cat. No.: HY-120957: FAQs
Data Sheet Handling Instructions

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AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.

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AMC Arachidonoyl Amide Chemical Structure

CAS No. : 862913-13-1

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Description	AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.
Molecular Weight	461.64
Formula	C₃₀H₃₉NO₃
CAS No.	862913-13-1
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (259 KB) Handling Instructions (2659 KB)
References	[1]. Cravatt, et al. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384, 83-87 (1996).

AMC Arachidonoyl Amide Related Classifications

Metabolic Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMC Arachidonoyl Amide862913-13-1AMC-AA 7-Amino-4-methyl coumarin-arachidonamideEndogenous MetaboliteInhibitorinhibitorinhibit

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AMC Arachidonoyl Amide (Synonyms: AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide)

AMC Arachidonoyl Amide Related Antibodies

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