Amentoflavone hexaacetate

Cat. No.: HY-124371: FAQs
Data Sheet Handling Instructions Technical Support

Amentoflavone hexaacetate is a 3,5-cyclic nucleotide phosphodiesterase inhibitor with antiplatelet aggregation activity. Amentoflavone hexaacetate can inhibit the aggregation of eluted human platelets induced by ADP or collagen. Amentoflavone hexaacetate can also inhibit the cAMP phosphodiesterase activity in human platelets. Amentoflavone hexaacetate can significantly increase the cAMP level of platelets in the presence of prostaglandin E1. Amentoflavone hexaacetate has anti-angiogenic and anti-metastatic effects.

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Amentoflavone hexaacetate Chemical Structure

CAS No. : 17482-37-0

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

Biological Activity
Purity & Documentation
References
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Description	Amentoflavone hexaacetate is a 3,5-cyclic nucleotide phosphodiesterase inhibitor with antiplatelet aggregation activity. Amentoflavone hexaacetate can inhibit the aggregation of eluted human platelets induced by ADP or collagen. Amentoflavone hexaacetate can also inhibit the cAMP phosphodiesterase activity in human platelets. Amentoflavone hexaacetate can significantly increase the cAMP level of platelets in the presence of prostaglandin E1. Amentoflavone hexaacetate has anti-angiogenic and anti-metastatic effects^[1].
Molecular Weight	790.68
Formula	C₄₂H₃₀O₁₆
CAS No.	17482-37-0
SMILES	O=C1C=C(OC2=C(C(OC(C)=O)=CC(OC(C)=O)=C12)C3=CC(C4=CC(C5=C(C=C(C=C5O4)OC(C)=O)OC(C)=O)=O)=CC=C3OC(C)=O)C6=CC=C(C=C6)OC(C)=O
Structure Classification	Flavonoids Biflavones
Initial Source	Plants Viburnaceae Viburnum lantana L.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Inhibition of human platelet cyclic AMP phosphodiesterase and of platelet aggregation by a hemisynthetic flavonoid, amentoflavone hexaacetate