2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. AMPA-IN-1

AMPA-IN-1 is a potent inhibitor of AMPA receptor. AMPA receptors are receptors that are widely expressed in the brain, and play a central role in the regulation of fast excitatory synaptic transmission and synaptic plasticity. AMPA-IN-1 has the potential for the research of various central diseases including epilepsy (extracted from patent WO2017082288A1, compound 14).

For research use only. We do not sell to patients.

AMPA-IN-1 Chemical Structure

AMPA-IN-1 Chemical Structure

CAS No. : 2097604-91-4

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AMPA-IN-1 Related Antibodies

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

AMPA-IN-1 is a potent inhibitor of AMPA receptor. AMPA receptors are receptors that are widely expressed in the brain, and play a central role in the regulation of fast excitatory synaptic transmission and synaptic plasticity. AMPA-IN-1 has the potential for the research of various central diseases including epilepsy (extracted from patent WO2017082288A1, compound 14)[1].

Molecular Weight

414.36

Formula

C23H12F2N4O2
CAS No.
SMILES

N#CC1=C(C2=CC3=C(N(C4=CC=CN=C4)C2=O)COC5=C3N=CC(F)=C5)C=CC=C1F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AMPA-IN-1 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMPA-IN-12097604-91-4iGluRIonotropic glutamate receptorsAMPA receptorsynaptic transmissionsynaptic plasticityepilepsyInhibitorinhibitorinhibit

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