2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Ampullosporin A

Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors.

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Ampullosporin A Chemical Structure

Ampullosporin A Chemical Structure

CAS No. : 197960-94-4

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Ampullosporin A Related Antibodies

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Description

Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors[1].

Molecular Weight

1622.95

Formula

C77H127N19O19
CAS No.
SMILES

CC(C)C[C@@H](CO)NC([C@H](CCC(N)=O)NC(C(C)(C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H](CCC(N)=O)NC(C(C)(C)NC([C@H](CC(C)C)NC(C(C)(C)NC(C(C)(C)NC([C@H](C)NC([C@@H](NC(C)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Structure Classification
Initial Source

Sepedonium ampullosporum HKI-0053
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Ampullosporin A Related Classifications

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Keywords:

Ampullosporin A197960-94-4iGluRIonotropic glutamate receptorsantipsychotic drugSchizophreniaSepedonium ampullosporum HKI-0053hyperactivitysocial behavior abnormalitiesInhibitorinhibitorinhibit

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