1. Vitamin D Related/Nuclear Receptor
  2. Androgen Receptor
  3. Androgen receptor-IN-3

Androgen receptor-IN-3 (Compound 22) is an androgen receptor inhibitor. Androgen receptor-IN-3 inhibits AR-driven transcriptional activity in LNCaP cells, with an IC50 of 5.04 μM.

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Androgen receptor-IN-3 Chemical Structure

Androgen receptor-IN-3 Chemical Structure

CAS No. : 926228-58-2

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Description

Androgen receptor-IN-3 (Compound 22) is an androgen receptor inhibitor. Androgen receptor-IN-3 inhibits AR-driven transcriptional activity in LNCaP cells, with an IC50 of 5.04 μM[1].

Cellular Effect
Cell Line Type Value Description References
LNCaP IC50
5.04 μM
Compound: 22
Inhibition of androgen receptor transcriptional activity in human LNCaP cells after 3 days by eGFP assay
Inhibition of androgen receptor transcriptional activity in human LNCaP cells after 3 days by eGFP assay
[PMID: 25062331]
Molecular Weight

276.35

Formula

C14H16N2O2S

CAS No.
SMILES

OCC1=C(C2=CC=CC=C2)N=C(N3CCOCC3)S1

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Androgen receptor-IN-3
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HY-131953
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