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  3. Anti-Trypanosoma cruzi agent-3

Anti-Trypanosoma cruzi agent-3 (Compound 7c) is an antiprotozoal agent.

For research use only. We do not sell to patients.

Anti-Trypanosoma cruzi agent-3 Chemical Structure

Anti-Trypanosoma cruzi agent-3 Chemical Structure

CAS No. : 2397639-23-3

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Description

Anti-Trypanosoma cruzi agent-3 (Compound 7c) is an antiprotozoal agent[1].

Cellular Effect
Cell Line Type Value Description References
L6 IC50
1.9 μM
Compound: 7c
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 trypomastigotes infected in rat L6 cells assessed as parasite growth inhibition measured after 96 hrs by inverted microscopy analysis
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 trypomastigotes infected in rat L6 cells assessed as parasite growth inhibition measured after 96 hrs by inverted microscopy analysis
[PMID: 31784198]
L6 IC50
7.1 μM
Compound: 7c
Cytotoxicity against rat L6 cells assessed as reduction in cell viability measured after 72 hrs by Alamar blue based inverted microscopy analysis
Cytotoxicity against rat L6 cells assessed as reduction in cell viability measured after 72 hrs by Alamar blue based inverted microscopy analysis
[PMID: 31784198]
In Vitro

Anti-Trypanosoma cruzi agent-3 (Compound 7c) shows antiprotozoal and cytotoxic activities with IC50 values of 2.7±0.3, 1.9±0.4, 0.9±0.0, 2.5±0.3 and 7.1±2.8 μM against T.b. rhodesiense, T. cruzi, L. donovani, P. falciparum and L6 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

547.62

Formula

C29H29N3O6S

CAS No.
SMILES

[H][C@@]1(OCC2=C1C=CC(OC)=C2OC)[C@]3(C4=C(OC)C5=C(OCO5)C=C4CCN3C(C6=CN=CC=C6)CN=C=S)[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Anti-Trypanosoma cruzi agent-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-Trypanosoma cruzi agent-3
Cat. No.:
HY-147765
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