2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 121

Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research.

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Antibacterial agent 121 Chemical Structure

Antibacterial agent 121 Chemical Structure

CAS No. : 474099-18-8

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Antibacterial agent 121 Related Antibodies

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Description

Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research[1].

In Vitro

Antibacterial agent 121 (0.2-200 µM; 24 h) inhibits M. tuberculosis H37Rv growth in bacterial culture[1].
Antibacterial agent 121 (0-200 µM; 24 h) inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC50 value of 4.1 µM[1].
Antibacterial agent 121 (6.25-200 µM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages[1].
Antibacterial agent 121 (25-100 µM, 4 d) inhibits M. tuberculosis M299 with an MIC50 value of 24.8 µM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 121 Related Antibodies

Cell Viability Assay[1]

Cell Line: M. tuberculosis H37Rv
Concentration: 0.2-200 µM
Incubation Time: 24 hours
Result: Inhibited Mtb H37Rv growth with MIC50 of 8.6 µM.

Cell Viability Assay[1]

Cell Line: RAW 264.7 macrophages and J774A.1 macrophages
Concentration: 6.25-200 µM
Incubation Time: 24 hours
Result: Showed IC50 values of 15.3 µM and 28.4 µM for TNF-α and IL-1β production, respectively.
Molecular Weight

346.44

Formula

C18H22N2O3S
CAS No.
SMILES

S=C(NC1=CC(OC)=C(OC)C(OC)=C1)NCCC2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 121 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 121474099-18-8Antibacterial agent121Antibacterial agent-121Bacterialanti-mycobacterial activityanti-inflammatory activityTuberculosisTBInhibitorinhibitorinhibit

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