1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 99

Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity.

For research use only. We do not sell to patients.

Antibacterial agent 99 Chemical Structure

Antibacterial agent 99 Chemical Structure

CAS No. : 2452306-13-5

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Description

Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity[1].

Cellular Effect
Cell Line Type Value Description References
HEK293 CC50
2.1 μg/mL
Compound: 7b
Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluorescence assay
Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluorescence assay
[PMID: 32619924]
In Vitro

Antibacterial agent 99 (compound 7b) shows antimicrobial activity with MIC of 8, 8, 16 μg/mL for Sa - Staphylococcus aureus (MRSA) ATCC 43300, Ca - Candida albicansATCC 90028, Cn - Cryptococcus neoformans H99 ATCC 208821, respectively[1].
Antibacterial agent 99 shows cytotoxicity with an CC50 of 2.1 μg/mL for HEK293 cells, and haemolytic activity with an HC10 of >32 μg/mL for human red blood cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

459.42

Formula

C27H27BrN2

CAS No.
SMILES

CC1=CC=C(C=C1)[N+]2=C3N(CCCCC3)C(C4=CC=C(C=C4)C5=CC=CC=C5)=C2.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Antibacterial agent 99 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antibacterial agent 99
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HY-146059
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