Acetyl-p53 (Lys370) Antibody

Acetyl-p53 (Lys370) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 44 kDa, targeting to Acetyl-p53 (Lys370). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

Acetyl-p53 (Lys370): This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Free

7157

Predicted band size: 44 kDa

affinity purified

Non-conjugated

Acetylated

Cell Biology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P04637

WB: 1:500-1:1,000 ;IF: 1:50-1:200 ;IP: 1:20

WB, ICC/IF, IP

Liquid

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Synthetic peptide corresponding to residues surrounding Lys370 of Human p53.The exact sequence is proprietary to MCE.