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  4. HSD11B1 Antibody (YA3376)

HSD11B1 Antibody (YA3376)

Cat. No.: HY-P83631
COA User Guide for Antibodies Technical Support

HSD11B1 Antibody (YA3376) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3376), targeting HSD11B1, with a predicted molecular weight of 32 kDa (observed band size: 32 kDa). HSD11B1 Antibody (YA3376) can be used for WB, IHC-P experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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Description

HSD11B1 Antibody (YA3376) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3376), targeting HSD11B1, with a predicted molecular weight of 32 kDa (observed band size: 32 kDa). HSD11B1 Antibody (YA3376) can be used for WB, IHC-P experiment in human, mouse, rat background.

Background

The protein encoded by The related gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in The related gene has been associated with obesity and insulin resistance in children. Mutations in The related gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Gene ID

3290

Synonyms
11-DH; 11-beta-HSD1; HSD11B1; HSD11; HSD11L; 11 beta HSD1
Molecular Weight

Predicted band size: 32 kDa; Observed band size: 32 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P28845

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100

Application

WB, IHC-P

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human HSD11B1

Documentation

HSD11B1 Antibody (YA3376) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HSD11B1 Antibody (YA3376)
Cat. No.:
HY-P83631
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