IL-10 Antibody

IL-10 Antibody is an unconjugated, approximately 18 kDa, rabbit-derived, anti-IL-10 monoclonal antibody. IL-10 Antibody can be used for: WB, ICC, FC expriments in human background without labeling.

The protein encoded by The related gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. The cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. The cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of The cytokine as an essential immunoregulator in the intestinal tract. Mutations in The related gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

3586

Predicted band size: 18kDa

affinity purified

Secreted.

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human

P22301

WB: 1/500-1/1000; IF: 1/50-1/200; FC: 1/50-1/100

WB, ICC/IF, FC

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human IL10.