Metabotropic Glutamate Receptor 3 Antibody (YA2977)

Metabotropic Glutamate Receptor 3 Antibody (YA2977) is a biotin-conjugated non-conjugated IgG antibody, targeting Metabotropic Glutamate Receptor 3, with a predicted molecular weight of 99 kDa (observed band size: 330 kDa). Metabotropic Glutamate Receptor 3 Antibody (YA2977) can be used for WB experiment in human, mouse, rat background.

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

2913

Predicted band size: 99 kDa; Observed band size: 330 kDa

Affinity Purified

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q14832

WB: 1/500-1/1000

WB

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human mGluR3