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  4. Metabotropic Glutamate Receptor 3 Antibody (YA2977)

Metabotropic Glutamate Receptor 3 Antibody (YA2977)

Cat. No.: HY-P83232
User Guide for Antibodies Technical Support

Metabotropic Glutamate Receptor 3 Antibody (YA2977) is a biotin-conjugated non-conjugated IgG antibody, targeting Metabotropic Glutamate Receptor 3, with a predicted molecular weight of 99 kDa (observed band size: 330 kDa). Metabotropic Glutamate Receptor 3 Antibody (YA2977) can be used for WB experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL Ask For Quote & Lead Time
50 μL Ask For Quote & Lead Time
100 μL Ask For Quote & Lead Time

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Description

Metabotropic Glutamate Receptor 3 Antibody (YA2977) is a biotin-conjugated non-conjugated IgG antibody, targeting Metabotropic Glutamate Receptor 3, with a predicted molecular weight of 99 kDa (observed band size: 330 kDa). Metabotropic Glutamate Receptor 3 Antibody (YA2977) can be used for WB experiment in human, mouse, rat background.

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Gene ID

2913

Synonyms
GLUR3; GPRC1C; GRM3; MGlu3; mGluR3
Molecular Weight

Predicted band size: 99 kDa; Observed band size: 330 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Neuroscience

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

Q14832

Dilution Ratio

WB: 1/500-1/1000

Application

WB

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human mGluR3

Documentation

Metabotropic Glutamate Receptor 3 Antibody (YA2977) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Metabotropic Glutamate Receptor 3 Antibody (YA2977)
Cat. No.:
HY-P83232
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