Notch4 Antibody (YA2557)

Notch4 Antibody (YA2557) is a biotin-conjugated non-conjugated IgG antibody, targeting Notch4, with a predicted molecular weight of 210 kDa (observed band size: 36 kDa). Notch4 Antibody (YA2557) can be used for WB experiment in human background.

The related gene encodes a member of the NOTCH family of proteins. Members of The Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to related generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. The receptor may play a role in vascular, renal and hepatic development. Mutations in The related gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

4855

Predicted band size: 210 kDa; Observed band size: 36 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q99466

WB: 1/500-1/1000

WB

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human NOTCH4