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  4. Phospho-Bad (Ser112) Antibody (YA3099)

Phospho-Bad (Ser112) Antibody (YA3099)

Cat. No.: HY-P83354
User Guide for Antibodies

Phospho-Bad (Ser112) Antibody (YA3099) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3099), targeting Phospho-Bad (Ser112), with a predicted molecular weight of 18 kDa (observed band size: 23 kDa). Phospho-Bad (Ser112) Antibody (YA3099) can be used for WB, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-Bad (Ser112) Antibody (YA3099) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3099), targeting Phospho-Bad (Ser112), with a predicted molecular weight of 18 kDa (observed band size: 23 kDa). Phospho-Bad (Ser112) Antibody (YA3099) can be used for WB, IP experiment in human, mouse, rat background.

Background

The protein encoded by The related gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. The protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of The protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of The protein. Alternative splicing of The related gene results in two transcript variants which encode the same isoform.

Gene ID

572

Synonyms
BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
Molecular Weight

Predicted band size: 18 kDa; Observed band size: 23 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Phosphorylated

Research Field

Cell Biology

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

Q92934

Dilution Ratio

WB: 1/500-1/1000;IP: 1/20

Application

WB, IP

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Bad

Documentation

Phospho-Bad (Ser112) Antibody (YA3099) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phospho-Bad (Ser112) Antibody (YA3099)
Cat. No.:
HY-P83354
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