Phospho-PKR (Thr446) Antibody (YA1026)

Cat. No.: HY-P81299A: FAQs
Data Sheet SDS COA User Guide for Antibodies

Phospho-PKR (Thr446) Antibody (YA1026) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1026), targeting Phospho-PKR (Thr446), with a predicted molecular weight of 62 kDa (observed band size: 62 kDa). Phospho-PKR (Thr446) Antibody (YA1026) can be used for WB, IHC-P, IP, ChIP experiment in human background.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
10 μL	$70	In-stock	Estimated Time of Arrival: December 31
50 μL	$185	In-stock	Estimated Time of Arrival: December 31
100 μL	$300	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	Phospho-PKR (Thr446) Antibody (YA1026) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1026), targeting Phospho-PKR (Thr446), with a predicted molecular weight of 62 kDa (observed band size: 62 kDa). Phospho-PKR (Thr446) Antibody (YA1026) can be used for WB, IHC-P, IP, ChIP experiment in human background.
Background	The protein encoded by The related gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. The protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.
Gene ID	5610
Synonyms	EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Molecular Weight	Predicted band size: 62 kDa; Observed band size: 62 kDa
Purity	Affinity Chromatography
Conjugation	Non-conjugated
Modification	Phosphorylated
Research Field	Signal Transduction
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human
SwissProt ID	P19525
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/50;ChIP: 1/20
Application	WB, IHC-P, IP, ChIP
Appearance	Liquid
Formulation	Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human Phospho-PKR (T446)
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

Phospho-PKR (Thr446) Antibody (YA1026) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-PKR (Thr446) Antibody (YA1026)

Biological Activity

Technical Parameters

Properties

Documentation

Phospho-PKR (Thr446) Antibody (YA1026) Related Classifications

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