SHP1 Antibody (YA1044)

SHP1 Antibody (YA1044) is a mouse-derived non-conjugated IgG2a antibody (Clone NO.: YA1044), targeting SHP1, with a predicted molecular weight of 68 kDa (observed band size: 68 kDa). SHP1 Antibody (YA1044) can be used for WB, IP experiment in human background.

The protein encoded by The related gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of The PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of The PTP with its substrates. The PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. The PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of The related gene, which encode distinct isoforms, have been reported.

5777

Predicted band size: 68 kDa; Observed band size: 68 kDa

Affinity Purified

Non-conjugated

Unmodified

Cell Biology

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

P29350

WB: 1/500-1/1000;IP: 1/20

WB, IP

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG2a

Endogenous

Purified recombinant human SHP-1 protein fragments expressed in E.coli.