2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 237

Anticancer agent 237 (compound 13) is a potent anticancer agent. Anticancer agent 237 shows cytotoxicity. Anticancer agent 237 induces apoptosis and cell cycle arrest at the S and G2/M phases.

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Anticancer agent 237 Chemical Structure

Anticancer agent 237 Chemical Structure

CAS No. : 17822-61-6

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Anticancer agent 237 Related Antibodies

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Description

Anticancer agent 237 (compound 13) is a potent anticancer agent. Anticancer agent 237 shows cytotoxicity. Anticancer agent 237 induces apoptosis and cell cycle arrest at the S and G2/M phases[1].

In Vitro

Anticancer agent 237 (compound 13) (48 h) induces apoptosis and cell cycle arrest at the S and G2/M phases in HCT-116, MCF-7 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 237 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: HCT-116, MCF-7 cells
Concentration: 0-100 µM
Incubation Time: 48 h
Result: Showed cytotoxicity with IC50s of 43.5, 62.4 µM for HCT-116, MCF-7 cells, respectively.

Apoptosis Analysis[1]

Cell Line: HCT-116, MCF-7 cells
Concentration: 43.5 for HCT-116 cells, 62.4 for MCF-7 cells µM
Incubation Time: 48 h
Result: Induced apoptosis with 2.24% of the population being in early apoptosis, 0.58% in late apoptosis, and 6.6% in the necrotic population in MCF-7 cells, led to 45.07% of the population being in early apoptosis, 0.42% in late apoptosis, and 0.02% necrotic population in HCT-116 cells.

Cell Cycle Analysis[1]

Cell Line: HCT-116, MCF-7 cells
Concentration: 0-100 µM
Incubation Time: 48 h
Result: Induced cell cycle arrest at the S and G2/M phases.
Molecular Weight

348.46

Formula

C18H24N2O3S
CAS No.
SMILES

O=S(C1=CC=C(C)C=C1)(NC(NC23CC4CC(C3)CC(C4)C2)=O)=O
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Storage

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References
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Anticancer agent 237 Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

Anticancer agent 23717822-61-6Anticancer agent237Anticancer agent-237ApoptosisanticancerG2/M phasesS phasesHCT-116MCF-7 cellscytotoxicityInhibitorinhibitorinhibit

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