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  4. Anticancer agent 51

Anticancer agent 51 (compound 3d) is a potent anticancer agent with an Ki of 731.62 nM. Anticancer agent 51 shows anticancer activity. Anticancer agent 51 has the potential for the research of prostate cancer.

For research use only. We do not sell to patients.

Anticancer agent 51 Chemical Structure

Anticancer agent 51 Chemical Structure

CAS No. : 2521777-38-6

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Anticancer agent 51 Related Antibodies

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Description

Anticancer agent 51 (compound 3d) is a potent anticancer agent with an Ki of 731.62 nM. Anticancer agent 51 shows anticancer activity. Anticancer agent 51 has the potential for the research of prostate cancer[1].

Cellular Effect
Cell Line Type Value Description References
DU-145 IC50
62.2 μM
Compound: 3d; SGK-606
Cytotoxicity against human DU-145 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human DU-145 cells assessed as reduction in cell viability by MTT assay
[PMID: 32998089]
LNCaP IC50
92.8 μM
Compound: 3d; SGK-606
Cytotoxicity against human LNCaP cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human LNCaP cells assessed as reduction in cell viability by MTT assay
[PMID: 32998089]
PC-3 IC50
64.3 μM
Compound: 3d; SGK-606
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability by MTT assay
[PMID: 32998089]
In Vitro

Anticancer agent 51 (compound 3d) shows anticancer activity with IC50s of 64.3, 62.2, 92.8 µM for PC-3, DU-145, LNCaP cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 51 Related Antibodies
Molecular Weight

447.47

Formula

C22H20F3N3O2S
CAS No.
SMILES

FC(F)(F)C(C=C1)=CC=C1NC(NNC([C@H](C2=CC3=C(C=C2)C=C(C=C3)OC)C)=O)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anticancer agent 51 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 512521777-38-6Anticancer agent51Anticancer agent-51OthersanticancerPC-3DU-145LNCaP cellsprostate cancerInhibitorinhibitorinhibit

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