2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 55

Anticancer agent 55 is a potent anticancer agent. Anticancer agent 55 shows anticancer activity via reducing the cell viability and cell migration in a dose-dependent manner. Anticancer agent 55 induces apoptosis. Anticancer agent 55 has the potential for the research of prostate cancer and breast cancer.

For research use only. We do not sell to patients.

Anticancer agent 55 Chemical Structure

Anticancer agent 55 Chemical Structure

CAS No. : 2408800-91-7

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Anticancer agent 55 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Anticancer agent 55 is a potent anticancer agent. Anticancer agent 55 shows anticancer activity via reducing the cell viability and cell migration in a dose-dependent manner. Anticancer agent 55 induces apoptosis. Anticancer agent 55 has the potential for the research of prostate cancer and breast cancer[1].

Cellular Effect
Cell Line Type Value Description References
MCF7 IC50
1.95 μM
Compound: 3h
Cytotoxicity against human MCF7 cells assessed as reduction cell viability incubated for 48 hrs by MTS assay
Cytotoxicity against human MCF7 cells assessed as reduction cell viability incubated for 48 hrs by MTS assay
[PMID: 31901746]
PC-3 IC50
1.18 μM
Compound: 3h
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
[PMID: 31901746]
In Vitro

Anticancer agent 55 (compound 3h) (0-100 μM; 48 h) inhibits cell viability with IC50s of 1.18 μM and 1.95 μM for PC-3, MCF-7 cells, respectively[1].
Anticancer agent 55 (0, 1, 3, 10 μM; 24 h) inhibits cell migration of PC-3 cells and MCF-7 cells in a dose-dependent manner[1].
Anticancer agent 55 (0, 1, 3, 10 μM; 12, 24 h) induces apoptosis by increases the caspase-3 activity and cleaved PARP levels[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 55 Related Antibodies

Cell Viability Assay[1]

Cell Line: PC-3, MCF-7 cells
Concentration: 0-100 µM
Incubation Time: 48 h
Result: Significantly inhibited cell viability of PC-3, MCF-7 cells with IC50s of 1.18 µM and 1.95 µM, respectively.

Apoptosis Analysis[1]

Cell Line: PC-3, MCF-7 cells
Concentration: 0, 1, 3, 10 µM
Incubation Time: PC-3 for 12 h; MCF-7 for 24 h
Result: Induced apoptosis by increased the caspase-3 activity in a concentration-dependent manner.

Western Blot Analysis[1]

Cell Line: PC-3, MCF-7 cells
Concentration: 0, 1, 3, 10 µM
Incubation Time: PC-3 for 12 h; MCF-7 for 24 h
Result: Increased cleaved PARP levels in a dose-dependent manner in PC-3 and MCF-7 cells.
Molecular Weight

596.28

Formula

C28H21Br2FN2O2
CAS No.
SMILES

O=C(C1=CC=CC=C1)C[N+]2=CC3=CC=CN3[C@@H](C2C4=CC=C(C=C4)Br)C(C5=CC=C(C=C5)F)=O.[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Anticancer agent 55 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 552408800-91-7Anticancer agent55Anticancer agent-55ApoptosisPC-3MCF-7 cellsmigrationapoptosisanticancercaspase-3cleaved PARPprostate cancerbreast cancerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Anticancer agent 55
Cat. No.:
HY-146433
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.