2. Anti-infection
  3. Bacterial
  4. Api137 TFA

Api137 TFA is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 TFA inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Api137 TFA Chemical Structure

Api137 TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Api137 TFA:

Api137 TFA Related Antibodies

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Description

Api137 TFA is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 TFA inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain[1][2].

Molecular Weight

2291.71 (free acid)

Formula

C104H171N37O22.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

N,N,N',N'-Tetramethylguanidino-{Orn}-Asn-Asn-Arg-Pro-Val-Tyr-Ile-Pro-Arg-Pro-Arg-Pro-Pro-His-Pro-Arg-Leu
Sequence Shortening

N,N,N',N'-Tetramethylguanidino-{Orn}-NNRPVYIPRPRPPHPRL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
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Api137 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Api137Api 137Api-137Bacterialantimicrobialtranslationprotein synthesis70S ribosomeInhibitorinhibitorinhibit

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Api137 TFA
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HY-P5723A
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