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  4. Apilimod hydrochloride

Apilimod hydrochloride  (Synonyms: STA 5326 hydrochloride; LAM-002A (free base) hydrochloride; AIT-101 hydrochloride)

Cat. No.: HY-14644B
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Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.

For research use only. We do not sell to patients.

Apilimod hydrochloride Chemical Structure

Apilimod hydrochloride Chemical Structure

CAS No. : 870087-37-9

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Apilimod hydrochloride Related Antibodies

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Description

Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.

Molecular Weight

491.41

Formula

C23H28Cl2N6O2
CAS No.
SMILES

CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Apilimod hydrochloride Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apilimod870087-37-9STA 5326LAM-002A free baseAIT-101STA5326STA-5326AIT101AIT 101OthersInhibitorinhibitorinhibit

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