2. Metabolic Enzyme/Protease Apoptosis
  3. Phosphodiesterase (PDE) Apoptosis TNF Receptor
  4. Apremilast (Standard)

Apremilast (Standard) is the analytical standard of Apremilast. This product is intended for research and analytical applications. Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM.

For research use only. We do not sell to patients.

Apremilast (Standard) Chemical Structure

Apremilast (Standard) Chemical Structure

CAS No. : 608141-41-9

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Description
Molecular Weight

460.50

Formula

C22H24N2O7S
CAS No.
SMILES

CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OCC)=C3)CS(=O)(C)=O)=O)=C1C2=O)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Apremilast (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apremilast (Standard)608141-41-9Phosphodiesterase (PDE)ApoptosisTNF ReceptorTumor Necrosis Factor ReceptorTNFRorallyavailabletype-4cyclicnucleotidephosphodiesterasePDE-4,TNF-αlipopolysaccharideLPSPBMCInhibitorinhibitorinhibit

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