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  4. Aristolochic acid sodium salt

Aristolochic acid sodium salt  (Synonyms: Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate)

Cat. No.: HY-N0510A Purity: 99.37%
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Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.

For research use only. We do not sell to patients.

Aristolochic acid sodium salt Chemical Structure

Aristolochic acid sodium salt Chemical Structure

CAS No. : 10190-99-5

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1 mg USD 65 In-stock
5 mg USD 153 In-stock
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Based on 9 publication(s) in Google Scholar

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Description

Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.

Molecular Weight

363.25

Formula

C17H10NNaO7
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(O[Na])C1=CC2=C(OCO2)C3=C4C(C(OC)=CC=C4)=CC([N+]([O-])=O)=C31
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (27.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7529 mL 13.7646 mL 27.5293 mL
5 mM 0.5506 mL 2.7529 mL 5.5058 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.7529 mL 13.7646 mL 27.5292 mL 68.8231 mL
5 mM 0.5506 mL 2.7529 mL 5.5058 mL 13.7646 mL
10 mM 0.2753 mL 1.3765 mL 2.7529 mL 6.8823 mL
15 mM 0.1835 mL 0.9176 mL 1.8353 mL 4.5882 mL
20 mM 0.1376 mL 0.6882 mL 1.3765 mL 3.4412 mL
25 mM 0.1101 mL 0.5506 mL 1.1012 mL 2.7529 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Aristolochic acid sodium salt Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aristolochic acid10190-99-5Aristolochic acid ITR 1736 Sodium aristolochateTR1736TR-1736Biochemical Assay Reagentsbiochemical assayreagentInhibitorinhibitorinhibit

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