2. Click Chemistry
  3. Alkynes
  4. ARN14686

ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM). ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe.

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ARN14686 Chemical Structure

ARN14686 Chemical Structure

CAS No. : 1628345-10-7

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Description

ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM). ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe[1].

Molecular Weight

280.36

Formula

C15H24N2O3
CAS No.
SMILES

O=C(OCCCCCCCCCC#C)N[C@H]1CNC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ARN14686 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ARN146861628345-10-7ARN 14686ARN-14686Othersclick-chemistryN-Acylethanolamine acid amidaseNAAAInhibitorinhibitorinhibit

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