2. Anti-infection
  3. HIV
  4. Atevirdine

Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication.

For research use only. We do not sell to patients.

Atevirdine Chemical Structure

Atevirdine Chemical Structure

CAS No. : 136816-75-6

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1 mg USD 208 In-stock
5 mg USD 520 In-stock
10 mg USD 730 In-stock
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Based on 1 publication(s) in Google Scholar

Atevirdine Related Antibodies

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HIV HIV-1 HIV-2

  • Biological Activity

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Description

Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication[1].

Cellular Effect
Cell Line Type Value Description References
CEM-SS EC50
10 x 10-4 μM
Compound: Atevirdine
Antiviral activity against HIV infected in human CEM-SS cells assessed as inhibition of virus induced cell killing by XTT assay
Antiviral activity against HIV infected in human CEM-SS cells assessed as inhibition of virus induced cell killing by XTT assay
[PMID: 19345581]
Molecular Weight

379.46

Formula

C21H25N5O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(N1CCN(C2=NC=CC=C2NCC)CC1)C(N3)=CC4=C3C=CC(OC)=C4
Shipping

Shipping with dry ice.
Storage

-80°C
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (329.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6353 mL 13.1766 mL 26.3532 mL
5 mM 0.5271 mL 2.6353 mL 5.2706 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6353 mL 13.1766 mL 26.3532 mL 65.8831 mL
5 mM 0.5271 mL 2.6353 mL 5.2706 mL 13.1766 mL
10 mM 0.2635 mL 1.3177 mL 2.6353 mL 6.5883 mL
15 mM 0.1757 mL 0.8784 mL 1.7569 mL 4.3922 mL
20 mM 0.1318 mL 0.6588 mL 1.3177 mL 3.2942 mL
25 mM 0.1054 mL 0.5271 mL 1.0541 mL 2.6353 mL
30 mM 0.0878 mL 0.4392 mL 0.8784 mL 2.1961 mL
40 mM 0.0659 mL 0.3294 mL 0.6588 mL 1.6471 mL
50 mM 0.0527 mL 0.2635 mL 0.5271 mL 1.3177 mL
60 mM 0.0439 mL 0.2196 mL 0.4392 mL 1.0981 mL
80 mM 0.0329 mL 0.1647 mL 0.3294 mL 0.8235 mL
100 mM 0.0264 mL 0.1318 mL 0.2635 mL 0.6588 mL
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Atevirdine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atevirdine136816-75-6HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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