2. One-stop Drug Screening
  3. Screening Libraries
  4. Bioactive Compound Series
  5. Drug Repurposing Series
  6. Clinical Compound Library Plus
Clinical Compound Library Plus

Cat. No.: HY-L026P

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication, such as lower risk and less investment. Clinical drugs have confirmed bioactivities, clear mechanisms and high safety that are suitable for drug repurposing.

MCE owns a unique collection of 3,189 clinical compounds that refer to various research areas including anti-cancer, anti-infection, anti-inflammation, nervous disease. Those compounds are of detailed information on clinical development status, research area, targets, etc. Clinical Compound Library Plus, with powerful screening capability, further complements Clinical Compound Library (HY-L026) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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  • Composition

Description & Advantages

•   A unique collection of 3,189 clinical compounds for high throughput screening (HTS) and high content screening (HCS).

•   Research areas include anticancer, anti-infection, anti inflammation, nervous disease, and more.

•   A useful tool for drug repurposing.

•   Currently in clinical stage, some are withdrawn or terminated.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 3,189 clinical compounds supplied as pre-dissolved Solutions or Solid
Solution: 2,302 compounds supplied in 10 mM solution, 53 compounds supplied in 2 mM solution, 12 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

VEGFR (71)

EGFR (62)

PI3K (62)

CDK (54)

HIV (48)

FGFR (40)

iGluR (38)

JAK (36)

mTOR (35)

PPAR (35)

HCV (33)

FLT3 (32)

HDAC (31)

PDGFR (30)

Akt (29)

CCR (29)

Btk (27)

CXCR (25)

nAChR (23)

MMP (22)

HSP (21)

mGluR (20)

PARP (20)

c-Kit (19)

GCGR (19)

COX (18)

c-Fms (17)

ERK (17)

HBV (17)

mAChR (17)

MEK (16)

Src (16)

Raf (15)

CFTR (14)

Syk (14)

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Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Clinical Compound Library Plus
    Cat. No.:
    HY-L026P
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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