2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. ATR-IN-16

ATR-IN-16 (compound 46) is a potent ATR kinase inhibitor. ATR-IN-16 shows good anticancer activity in LoVo cells, with an IC50 of 410 nM.

For research use only. We do not sell to patients.

ATR-IN-16 Chemical Structure

ATR-IN-16 Chemical Structure

CAS No. : 2756589-62-3

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ATR-IN-16 Related Antibodies

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ATM ATR

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Description

ATR-IN-16 (compound 46) is a potent ATR kinase inhibitor. ATR-IN-16 shows good anticancer activity in LoVo cells, with an IC50 of 410 nM[1].

IC50 & Target

ATR

 

Molecular Weight

367.45

Formula

C19H25N7O
CAS No.
SMILES

CC1=NNC(NC2=CC(C3=C(C=NN3C)C)=CC(N4CCOC[C@H]4C)=N2)=C1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ATR-IN-16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATR-IN-162756589-62-3ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedanticancer activityLoVo cellsInhibitorinhibitorinhibit

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