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  4. AZD-6605

AZD-6605 is a potent, reversible inhibitor of MMP2, MMP9, MMP12 and MMP13 with excellent selectivity. During drug development, AZD-6605 was optimized for activity, solubility and DMPK properties against MMP13 by replacing the zinc hydroxide binding group associated with historical inhibitors.

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AZD-6605 Chemical Structure

AZD-6605 Chemical Structure

CAS No. : 893556-15-5

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AZD-6605 Related Antibodies

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Description

AZD-6605 is a potent, reversible inhibitor of MMP2, MMP9, MMP12 and MMP13 with excellent selectivity. During drug development, AZD-6605 was optimized for activity, solubility and DMPK properties against MMP13 by replacing the zinc hydroxide binding group associated with historical inhibitors[1].

Molecular Weight

483.43

Formula

C18H21F4N3O6S
CAS No.
SMILES

O=C1NC([C@](C)(N1)CS(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(C(F)F)F)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AZD-6605 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZD-6605893556-15-5AZD6605AZD 6605OthersInhibitorinhibitorinhibit

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