2. GPCR/G Protein
  3. Bradykinin Receptor
  4. B4148

B4148 is a selective competitive bradykinin (BK) antagonist that significantly inhibits BK-induced hypotension in rats. In a rat model of endotoxin shock induced by Escherichia coli lipopolysaccharide, B4148 significantly attenuated the decrease in mean arterial blood pressure compared with the control group.

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B4148 Chemical Structure

B4148 Chemical Structure

CAS No. : 103412-37-9

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B4148 Related Antibodies

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Description

B4148 is a selective competitive bradykinin (BK) antagonist that significantly inhibits BK-induced hypotension in rats. In a rat model of endotoxin shock induced by Escherichia coli lipopolysaccharide, B4148 significantly attenuated the decrease in mean arterial blood pressure compared with the control group[1].

Molecular Weight

1394.67

Formula

C62H95N19O14S2
CAS No.
Sequence

Lys-Lys-Arg-{Hyp}-Pro-Gly-{Thi}-Ser-Phe-{Thi}-Arg
Sequence Shortening

KKR-{Hyp}-PG-{Thi}-SF-{Thi}-R
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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B4148 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

B4148103412-37-9B 4148B-4148Bradykinin ReceptorInhibitorinhibitorinhibit

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