Benzocaine hydrochloride

Cat. No.: HY-Y0258A Purity: 99.31%: FAQs
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Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain, that acts on voltage-gated Na⁺ channels at a common receptor, with an IC₅₀ value of 0.8 mM at +30 mV. Additionally, Benzocaine (hydrochloride) non-competitively inhibits Ca-ATPase binding with Ca²⁺, with an IC₅₀ of 47.1 mM. Benzocaine (hydrochloride) can be used in research within the field of neuromuscular regulation.

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Benzocaine hydrochloride Chemical Structure

CAS No. : 23239-88-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Benzocaine hydrochloride:

Benzocaine In-stock

1 Publications Citing Use of MCE Benzocaine hydrochloride

•Stem Cell Res Ther. 2021 Feb 4;12(1):107. [Abstract]

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Biological Activity
Purity & Documentation
References
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Description	Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain, that acts on voltage-gated Na⁺ channels at a common receptor, with an IC₅₀ value of 0.8 mM at +30 mV. Additionally, Benzocaine (hydrochloride) non-competitively inhibits Ca-ATPase binding with Ca²⁺, with an IC₅₀ of 47.1 mM. Benzocaine (hydrochloride) can be used in research within the field of neuromuscular regulation^[1]^[2]^[3].
Molecular Weight	201.65
Formula	C₉H₁₂ClNO₂
CAS No.	23239-88-5
Appearance	Solid
Color	White to off-white
SMILES	O=C(OCC)C1=CC=C(N)C=C1.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation	Purity: 99.31% Select Batch: Data Sheet (268 KB) SDS (252 KB) COA (246 KB) LCMS (98 KB) Handling Instructions (2659 KB)
References	[1]. Wang GK, et al. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435(2):293-302. [Content Brief] [2]. Davis JA, et al. Benzocaine-induced methemoglobinemia attributed to topical application of the anesthetic in several laboratory animal species. Am J Vet Res. 1993 Aug;54(8):1322-6. [Content Brief] [3]. Di Croce D, et al. Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1163-70. [Content Brief]