2. Cell Cycle/DNA Damage Epigenetics
  3. Aurora Kinase
  4. BET/Aurora kinase-IN-1

BET/Aurora kinase-IN-1 (Compound 38) is a dual BET/Aurora kinase inhibitor. BET/Aurora kinase-IN-1 shows antiproliferative activities on diverse cancer cell lines and favorable antitumor efficacy in renal cell cancer and colon cancer xenograft models with tumor growth inhibition (TGI) of 45.99% and 53.06%, respectively.

For research use only. We do not sell to patients.

BET/Aurora kinase-IN-1 Chemical Structure

BET/Aurora kinase-IN-1 Chemical Structure

CAS No. : 2674064-32-3

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BET/Aurora kinase-IN-1 Related Antibodies

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Description

BET/Aurora kinase-IN-1 (Compound 38) is a dual BET/Aurora kinase inhibitor. BET/Aurora kinase-IN-1 shows antiproliferative activities on diverse cancer cell lines and favorable antitumor efficacy in renal cell cancer and colon cancer xenograft models with tumor growth inhibition (TGI) of 45.99% and 53.06%, respectively[1].

Molecular Weight

463.55

Formula

C25H30FN7O
CAS No.
SMILES

CN(C1=O)C(C=CC(NC2=NC=C(C(C3=C(N(N=C3C4CC4)C)C)=N2)F)=C5)=C5N([C@@H]1C)C(C)C
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Purity & Documentation
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BET/Aurora kinase-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BET/Aurora kinase-IN-12674064-32-3Aurora KinaseBET/Aurora kinaseantiproliferativeantitumorInhibitorinhibitorinhibit

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