2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. BHEPN

BHEPN is an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). BHEPN has inhibition of VEGFR-2 with an IC50 value of 0.320 μM. BHEPN also exhibits remarkable cytotoxic effects against HepG2 and MCF-7 cancer cell lines, with IC50 values of 0.19 μM and 1.18 μM, respectively. BHEPN can be used for anticancer research.

For research use only. We do not sell to patients.

BHEPN Chemical Structure

BHEPN Chemical Structure

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BHEPN Related Antibodies

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Description

BHEPN is an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). BHEPN has inhibition of VEGFR-2 with an IC50 value of 0.320 μM. BHEPN also exhibits remarkable cytotoxic effects against HepG2 and MCF-7 cancer cell lines, with IC50 values of 0.19 μM and 1.18 μM, respectively. BHEPN can be used for anticancer research[1].

IC50 & Target

IC50: 0.320 μM (VEGFR-2); 0.19 μM (HepG2); 1.18 μM (MCF-7)[1]
Molecular Weight

437.29

Formula

C21H17BrN4O2
SMILES

O=C(NC1=CC=CC(/C(C)=N/NC(C2=CC=C(Br)C=C2)=O)=C1)C3=CN=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BHEPN Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BHEPNVEGFRVascular endothelial growth factor receptorvascular endothelial growth factor receptor-2 (VEGFR-2)HepG2 cancer cell linesMCF-7 cancer cell linesanticancerInhibitorinhibitorinhibit

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