2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. BIMAX2

BIMAX2 is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence.

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BIMAX2 Chemical Structure

BIMAX2 Chemical Structure

CAS No. : 1105053-46-0

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BIMAX2 Related Antibodies

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Description

BIMAX2 is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence[1].

Molecular Weight

3561.98

Formula

C146H254N64O41
CAS No.
Sequence

Arg-Arg-Arg-Arg-Arg-Arg-Lys-Arg-Lys-Arg-Glu-Trp-Asp-Asp-Asp-Asp-Asp-Pro-Pro-Lys-Lys-Arg-Arg-Arg-Leu-Asp
Sequence Shortening

RRRRRRKRKREWDDDDDPPKKRRRLD
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BIMAX2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIMAX21105053-46-0BIMAX 2BIMAX-2OthersNuclear localization signalnuclear import proteincargo proteinRBBP-4cell senescencenuclear import efficiencyInhibitorinhibitorinhibit

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