Acyl-coenzyme A synthetase ACSM3, mitochondrial

Definition:

Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms (By similarity).

References:

[1]. Naoharu Iwai, et al. Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension. Circulation. 2002 Jan 1;105(1):41-7. [Content Brief]

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