Afibrinogenemia

Definition:

Congenital fibrinogen defects caused by mutation of any of fibrinogen genes (FGA, FGB, and FGG) include both quantitative defects (type I deficiencies or afibrinogenemia) and qualitative defects (type II deficiencies or dysfibrinogenemia). Fibrinogen deficiency and dysfunction are associated with bleeding or thrombosis.

References:

[1]. M Hill, et al. Diagnosis, clinical features and molecular assessment of the dysfibrinogenaemias. Haemophilia. 2008 Sep;14(5):889-97. [Content Brief]

[2]. Marguerite Neerman-Arbez, et al. Molecular basis of fibrinogen deficiency. Pathophysiol Haemost Thromb. 2006;35(1-2):187-98. [Content Brief]

[3]. R Asselta, et al. The molecular basis of quantitative fibrinogen disorders. J Thromb Haemost. 2006 Oct;4(10):2115-29. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.